Many neurons display bistability--coexistence of two firing modes such as bursting and tonic spiking or tonic spiking and silence.Bistability has been proposed to endow neurons with richer forms of information processing in general and to be involved in short-term memory in particular strict by allowing a brief signal to elicit long-lasting changes
Early Photometric and Spectral Evolution of Nova Cygni 2014 (V2659 Cyg)
We present optical spectroscopic and UBV (RI)C photometric observations of Nova Cygni 2014 (V2659 Cyg) from its rebrightening to the Wooden Shape Sorting nebular stage.After the first maximum, the nova underwent several irregular flare-like rebrightenings, with amplitudes up to two magnitudes, accompanied with spectral changes.During the bright sta
Towards pragmatism in climate risk analysis and adaptation
The Asia-Pacific region is extremely vulnerable to climate variability and change.This reflects high ORG CALENDULA exposure to hydroclimatic hazards such as tropical cyclones, floods, droughts, and heatwaves.Rapidly growing cities and low-lying coastal zones/estuaries also face threats from sea level rise and storm surges.However, climate model pro
Patient-Reported Outcomes of Kinematic vs Mechanical Alignment in Total Knee Arthroplasty: A Systematic Review and Meta-analysis of Randomized Controlled Trials
Background: Total knee arthroplasty (TKA) is an effective treatment method for severe osteoarthritis of the knee.Poor alignment of a knee replacement has been associated with suboptimal clinical results.Traditionally, mechanical alignment (MA) has been considered the gold standard.In light of reports of decreased satisfaction with TKA, a new techni